HSPB1 inhibitor J2 attenuates lung inflammation through direct modulation of Ym1 production and paracrine signaling

HSPB1 inhibitor J2 attenuates lung inflammation through direct modulation of Ym1 production and paracrine signaling

Heat shock protein beta-1 (HSPB1) is a multifaceted protein that controls cellular stress, modulates cell differentiation and development, and inhibits apoptosis of cancer cells. Increased HSPB1 expression is highly associated with poor outcomes in lung cancer by enhancing cell migration and invasio...

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Bibliographic Details
Main Authors: Areum Oh, Seulgi Jeon, Mi Gyeong Jeong, Hyo Kyeong Kim, Jio Kang, Yun-Sil Lee, Eun Sook Hwang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Antifibrosis
HSPB1
J2
M2 macrophages
STAT6
Ym1
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222101009X

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http://www.sciencedirect.com/science/article/pii/S075333222101009X

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