Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes

<p>Abstract</p> <p>Background</p> <p>Osteonecrosis of the femoral head is a common complication of high-dose glucocorticoid treatment. Intravascular thrombosis is thought to be associated with the ischemic state of the femoral head. Plasminogen activator inhibitor-1 (PA...

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Bibliographic Details
Main Authors: Baba Hideo, Fukushima Tatsuya, Goto Hisataka, Hozumi Akira, Osaki Makoto, Sakamoto Kazutaka, Shindo Hiroyuki
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/12/82