Thrombopoietin Protects Cardiomyocytes from Iron-Overload Induced Oxidative Stress and Mitochondrial Injury

Thrombopoietin Protects Cardiomyocytes from Iron-Overload Induced Oxidative Stress and Mitochondrial Injury

Background/Aims: Thalassaemia accompanied with iron-overload is common in Hong Kong. Iron-overload induced cardiomyopathy is the commonest cause of morbidity and mortality in patients with β-thalassaemia. Chronic iron-overload due to blood transfusion can cause cardiac failure. Decreased antioxidant...

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Bibliographic Details
Main Authors: Shing Chan, Godfrey Chifung Chan, Jieyu Ye, Qizhou Lian, Jianliang Chen, Mo Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
TPO
Fluorometry
Cytometry
Iron-overload
Cardiac Failure
Oxidative Stress
Online Access:http://www.karger.com/Article/FullText/430173

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