Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
Oligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and co...
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MDPI AG
2010-02-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/15/2/842/ |
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doaj-5fbb217c07be485ba6040c6016bd29122020-11-24T21:49:58ZengMDPI AGMolecules1420-30492010-02-0115284285610.3390/molecules15020842Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane ConjugatesWaclaw KolodziejskiKatarzyna NurzyńskaMarcin SobczakOligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and conjugates were elucidated by means of MALDI-TOF MS, NMR and IR studies. http://www.mdpi.com/1420-3049/15/2/842/aliphatic polyestersaliphatic polyurethanesring-opening polymerizationmacromolecular conjugatesprodrugs of norfloxacin |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Waclaw Kolodziejski Katarzyna Nurzyńska Marcin Sobczak |
| spellingShingle |
Waclaw Kolodziejski Katarzyna Nurzyńska Marcin Sobczak Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates Molecules aliphatic polyesters aliphatic polyurethanes ring-opening polymerization macromolecular conjugates prodrugs of norfloxacin |
| author_facet |
Waclaw Kolodziejski Katarzyna Nurzyńska Marcin Sobczak |
| author_sort |
Waclaw Kolodziejski |
| title |
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates |
| title_short |
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates |
| title_full |
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates |
| title_fullStr |
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates |
| title_full_unstemmed |
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates |
| title_sort |
seeking polymeric prodrugs of norfloxacin. part 2. synthesis and structural analysis of polyurethane conjugates |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2010-02-01 |
| description |
Oligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and conjugates were elucidated by means of MALDI-TOF MS, NMR and IR studies. |
| topic |
aliphatic polyesters aliphatic polyurethanes ring-opening polymerization macromolecular conjugates prodrugs of norfloxacin |
| url |
http://www.mdpi.com/1420-3049/15/2/842/ |
| work_keys_str_mv |
AT waclawkolodziejski seekingpolymericprodrugsofnorfloxacinpart2synthesisandstructuralanalysisofpolyurethaneconjugates AT katarzynanurzynska seekingpolymericprodrugsofnorfloxacinpart2synthesisandstructuralanalysisofpolyurethaneconjugates AT marcinsobczak seekingpolymericprodrugsofnorfloxacinpart2synthesisandstructuralanalysisofpolyurethaneconjugates |
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1725886175290327040 |