Barriers to antigenic escape by pathogens: trade-off between reproductive rate and antigenic mutability

<p>Abstract</p> <p>Background</p> <p>A single measles vaccination provides lifelong protection. No antigenic variants that escape immunity have been observed. By contrast, influenza continually evolves new antigenic variants, and the vaccine has to be updated frequently...

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Bibliographic Details
Main Authors: Bush Robin M, Frank Steven A
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/7/229

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