بررسی تأثیر ابتلا به پریودنتیت مزمن بر میزان بیان ژن TLR-2 و TLR-4 در بافت لثه ای

بررسی تأثیر ابتلا به پریودنتیت مزمن بر میزان بیان ژن TLR-2 و TLR-4 در بافت لثه ای

مقدمه: در عفونت‏های پریودنتال پیش نیاز شروع پاسخ‏های میزبان، شناخت پاتوژن‏‏ها توسط سیستم ایمنی میزبان می‏باشد. خانواده رسپتور‏های Toll-like (TLRs)، مسئول شناسایی ساختار‏های حفظ شده میکروبیال نظیر لیپوپلی ساکارید (LPS) باکتری‏ها می‏باشند و مسیر‏های سیگنال دهنده را که در نهایت منجر به پاسخ‏های ایمنی م...

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Bibliographic Details
Main Authors:	کاظم فاطمی, مهرداد رادور, عبدالرحیم رضایی, حمیدرضا عرب, هوشنگ رفعت پناه, حسن آذان گو خیاوی, یلدا دادپور
Format:	Article
Language:	fas
Published:	Mashhad University of Medical Sciences 2011-12-01
Series:	Journal of Mashhad Dental School
Subjects:	chronic periodontitis TLR-2 TLR-4 Real-time PCR
Online Access:	http://jmds.mums.ac.ir/pdf_950_9860b33d9a14274669cd5223d59a4884.html

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