Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability

Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability

Abstract Background The tumour microenvironment is essential for cancer progress and metastasis. Integrin-β5 (ITGB5), a member of the integrin family, has been implicated to mediate the interactions of cells with the extracellular matrix (ECM) and promote tumorigenesis in several malignancies. Howev...

Full description

Bibliographic Details
Main Authors: Zhikun Lin, Ruiping He, Haifeng Luo, Chang Lu, Zhen Ning, Yuanhang Wu, Chuanchun Han, Guang Tan, Zhongyu Wang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Integrin-β5
β-catenin
miR-185
Hepatocellular carcinoma
Online Access:http://link.springer.com/article/10.1186/s13046-018-0691-9

Internet

http://link.springer.com/article/10.1186/s13046-018-0691-9

Similar Items