Expression and Function of Organic Cation Transporter 2 in Pancreas

Expression and Function of Organic Cation Transporter 2 in Pancreas

Organic cation transporters (OCT) play an important role in mediating cellular uptake of several pharmaceuticals, such as the antidiabetic drug metformin and the platinum-derived chemotherapeutics. Since these drugs can also affect the pancreas, here it was investigated whether these transporters ar...

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Bibliographic Details
Main Authors:	Sandra Schorn, Ann-Kristin Dicke, Ute Neugebauer, Rita Schröter, Maren Friedrich, Stefan Reuter, Giuliano Ciarimboli
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	organic cation transporters glucose transporter glucose pancreas metformin
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.688885/full

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