Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury

Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury

Thrombomodulin (TM) is a single transmembrane, multidomain glycoprotein receptor for thrombin, and is best known for its role as a cofactor in a clinically important natural anticoagulant pathway. In addition to its anticoagulant function, TM has well-defined anti-inflammatory properties. Soluble TM...

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Bibliographic Details
Main Authors: Yuji Nozaki, Jinhai Ri, Kenji Sakai, Kaoru Niki, Masanori Funauchi, Itaru Matsumura
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
acute kidney injury
sepsis
apoptosis
cytokine
Online Access:https://www.mdpi.com/1422-0067/21/7/2519

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