Paroxysmal nocturnal hemoglobinuria: a study of 17 cases.
Retrospective analysis of 17 cases of paroxysmal nocturnal hemoglobinuria (PNH) was carried out. The presenting feature of anaemia and hemoglobin of less than 9 gm% were observed in all cases. Fever, jaundice and bleeding tendency were observed in 8, 8 and 7 cases respectively. Bone marro...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
1990-01-01
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| Series: | Journal of Postgraduate Medicine |
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| Online Access: | http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1990;volume=36;issue=1;spage=23;epage=6;aulast=Parab |
| Summary: | Retrospective analysis of 17 cases of paroxysmal nocturnal hemoglobinuria (PNH) was carried out. The presenting feature of anaemia and hemoglobin of less than 9 gm% were observed in all cases. Fever, jaundice and bleeding tendency were observed in 8, 8 and 7 cases respectively. Bone marrow examination revealed megaloblastic features, erythroid hyperplasia and hypocellularity in 8, 7 and 2 cases respectively. Fourteen cases were refractory to the treatment, while only 3 showed response. |
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| ISSN: | 0022-3859 0972-2823 |