A Putative Prohibitin-Calcium Nexus in β-Cell Mitochondria and Diabetes
The role of mitochondria in apoptosis is well known; however, the mechanisms linking mitochondria to the proapoptotic effects of proinflammatory cytokines, hyperglycemia, and glucolipotoxicity are not completely understood. Complex Ca2+ signaling has emerged as a critical contributor to these proapo...
Main Authors: | Gaurav Verma, Aparna Dixit, Craig S. Nunemaker |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2020/7814628 |
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