Design and synthesis of new esters of terpenoid alcohols as 15-lipoxygenase inhibitors
Objective(s): 15-Lipoxygenases are one of the iron-containing proteins capable of performing peroxidation of unsaturated fatty acids in animals and plants. The critical role of enzymes in the formation of inflammations, sensitivities, and some cancers has been demonstrated in mammals. The importance...
Main Authors: | Hamid Sadeghian, Seyed Mohammad Seyedi, Zeinab Jafari |
---|---|
Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2018-07-01
|
Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://ijbms.mums.ac.ir/article_10763_b671f07c65669017ad8668ab9b1956a5.pdf |
Similar Items
-
Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors
by: Sahar A. Ali, et al.
Published: (2020-01-01) -
Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors
by: Mina Mousavian, et al.
Published: (2020-08-01) -
Natural products isolated from Tetragonula carbonaria cerumen modulate free radical-scavenging and 5-lipoxygenase activities in vitro
by: Karina D. Hamilton, et al.
Published: (2017-04-01) -
Regulation of Tissue Inflammation by 12-Lipoxygenases
by: Abhishek Kulkarni, et al.
Published: (2021-05-01) -
A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages
by: Ryan G. Snodgrass, et al.
Published: (2018-08-01)