Involvement of ayu NOD2 in NF-κB and MAPK signaling pathways: Insights into functional conservation of NOD2 in antibacterial innate immunity

Involvement of ayu NOD2 in NF-κB and MAPK signaling pathways: Insights into functional conservation of NOD2 in antibacterial innate immunity

Nucleotide oligomerization domain 2 (NOD2) is a major cytoplasmic sensor for pathogens and is critical for the clearance of cytosolic bacteria in mammals. However, studies regarding NOD2, especially the initiated signaling pathways, are scarce in teleost species. In this study, we identified a NOD2...

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Bibliographic Details
Main Authors: Yi Ren, Shui-Fang Liu, Li Nie, Shi-Yu Cai, Jiong Chen
Format: Article
Language:English
Published: Science Press, PR China 2019-03-01
Series:Zoological Research
Subjects:
Ayu NOD2
NF-κB signaling
MAPK signaling
Inflammatory cytokines
Vibrio anguillarum infection
Online Access:http://www.zoores.ac.cn/EN/abstract/abstract3896.shtml

Internet

http://www.zoores.ac.cn/EN/abstract/abstract3896.shtml

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