The clinical significance of preoperative serum CEA, β-HCG and CXs detection in the diagnosis of non-small cell lung cancer

• Main Authors: Xian-Hua Yang, Juan Chen
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-01-01
• Series: Journal of Hainan Medical University
• Subjects: Non-small cell lung cancer; Carcinoembryonic antigen; β-human chorionic gonadotropin; Clinical stage; Prognosis
• Online Access: http://www.hnykdxxb.com/PDF/201601/87-90.pdf

Objective: To study the clinical significance of preoperative serum CEA, β-HCG and CXs detection in the diagnosis of non-small cell lung cancer and provide reference for clinical diagnosis and disease treatment. Methods: Non-small cell lung cancer patients treated in our hospital from April 2009 to April 2014 were analyzed. Correlation between preoperative serum CEA, β-HCG as well as Cxs and clinical stages as well as prognosis of non-small cell lung cancer was assayed. Healthy subjects in our hospital during the same period were taken as control group. Results: Serum CEA, β-HCG and Cxs had no obvious correlation with patients’ age and gender, but CEA and β-HCG had negative correlation with the clinical stages and prognosis of non-small cell lung cancer while Connexin43 had positive correlation with the clinical stages and prognosis of non-small cell lung cancer. Conclusions: Preoperative serum CEA combined with β-HCG and CXs detection can be taken as key molecules in clinical diagnosis and prognosis of non-small cell lung cancer.