Neutrophil activation identifies patients with active polyarticular gout

Neutrophil activation identifies patients with active polyarticular gout

Abstract Background Gout is the most prevalent inflammatory arthritis in developed countries. A gout flare is mediated by phagocytosis of monosodium urate crystals by macrophages and neutrophils leading to subsequent activation of neutrophils contributing to synovitis, local joint destruction, and s...

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Bibliographic Details
Main Authors: D. Vedder, M. Gerritsen, B. Duvvuri, R. F. van Vollenhoven, M. T. Nurmohamed, C. Lood
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Arthritis Research & Therapy
Subjects:
Gout
Crystal-induced arthritis
Neutrophils
Innate immunity
Disease activity
Online Access:http://link.springer.com/article/10.1186/s13075-020-02244-6

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http://link.springer.com/article/10.1186/s13075-020-02244-6

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