Efficacy and Safety of Eculizumab in the Treatment of Transplant-Associated Thrombotic Microangiopathy: A Systematic Review and Meta-Analysis

Efficacy and Safety of Eculizumab in the Treatment of Transplant-Associated Thrombotic Microangiopathy: A Systematic Review and Meta-Analysis

BackgroundTransplant-associated thrombotic microangiopathy (TA-TMA) is a dangerous and life-threatening complication in patients undergoing hematopoietic stem cell transplantation (HSCT). Eculizumab has been used in the treatment of TA-TMA, and several studies have confirmed the benefit of Eculizuma...

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Bibliographic Details
Main Authors:	Rui Zhang, Meng Zhou, Jiaqian Qi, Wenjing Miao, Ziyan Zhang, Depei Wu, Yue Han
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-01-01
Series:	Frontiers in Immunology
Subjects:	Eculizumab terminal complement inhibitor transplant-associated thrombotic microangiopathy hematopoietic stem cell transplantation efficacy safety
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.564647/full

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