Rhythms of Core Clock Genes and Spontaneous Locomotor Activity in Post-Status Epilepticus Model of Mesial Temporal Lobe Epilepsy

Rhythms of Core Clock Genes and Spontaneous Locomotor Activity in Post-Status Epilepticus Model of Mesial Temporal Lobe Epilepsy

The interaction of Mesial Temporal Lobe Epilepsy (mTLE) with the circadian system control is apparent from an oscillatory pattern of limbic seizures, daytime's effect on seizure onset and the efficacy of antiepileptic drugs. Moreover, seizures per se can interfere with the biological rhythm out...

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Bibliographic Details
Main Authors: Heloisa de Carvalho Matos, Bruna Del Vechio Koike, Wanessa dos Santos Pereira, Tiago G. de Andrade, Olagide W. Castro, Marcelo Duzzioni, Maheedhar Kodali, Joao P. Leite, Ashok K. Shetty, Daniel L. G. Gitaí
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
clock genes
epilepsy
seizure
spontaneous locomotor activity
circadian rhythm
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00632/full

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