On protocols and measures for the validation of supervised methods for the inference of biological networks

On protocols and measures for the validation of supervised methods for the inference of biological networks

Networks provide a natural representation of molecular biology knowledge, in particular to model relationships between biological entities such as genes, proteins, drugs, or diseases. Because of the effort, the cost, or the lack of the experiments necessary for the elucidation of these networks, com...

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Bibliographic Details
Main Authors: Marie eSchrynemackers, Robert eKueffner, Pierre eGeurts
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Genetics
Subjects:
Cross-validation
Biological network inference
supervised learning
evaluation protocols
ROC curves
precision-recall curves
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00262/full

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