Targeting Breast Cancer Metastasis

Targeting Breast Cancer Metastasis

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Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant improvement in current therapies in extending patient life, 30–40% of patients may eventually suffer from distant relapse and succumb to the disease. Consequently, a deeper understanding of the metastasis bio...

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Bibliographic Details
Main Authors: Xin Jin, Ping Mu
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.4137/BCBCR.S25460
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spelling doaj-5f368713296c40759c55f6f61a0cc57b2020-11-25T02:34:09ZengSAGE PublishingBreast Cancer: Basic and Clinical Research1178-22342015-01-019s110.4137/BCBCR.S25460Targeting Breast Cancer MetastasisXin Jin0Ping Mu1Institute for Medical Engineering & Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA.Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant improvement in current therapies in extending patient life, 30–40% of patients may eventually suffer from distant relapse and succumb to the disease. Consequently, a deeper understanding of the metastasis biology is key to developing better treatment strategies and achieving long-lasting therapeutic efficacies against breast cancer. This review covers recent breakthroughs in the discovery of various metastatic traits that contribute to the metastasis cascade of breast cancer, which may provide novel avenues for therapeutic targeting.https://doi.org/10.4137/BCBCR.S25460
collection DOAJ
language English
format Article
sources DOAJ
author Xin Jin
Ping Mu
spellingShingle Xin Jin
Ping Mu
Targeting Breast Cancer Metastasis
Breast Cancer: Basic and Clinical Research
author_facet Xin Jin
Ping Mu
author_sort Xin Jin
title Targeting Breast Cancer Metastasis
title_short Targeting Breast Cancer Metastasis
title_full Targeting Breast Cancer Metastasis
title_fullStr Targeting Breast Cancer Metastasis
title_full_unstemmed Targeting Breast Cancer Metastasis
title_sort targeting breast cancer metastasis
publisher SAGE Publishing
series Breast Cancer: Basic and Clinical Research
issn 1178-2234
publishDate 2015-01-01
description Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant improvement in current therapies in extending patient life, 30–40% of patients may eventually suffer from distant relapse and succumb to the disease. Consequently, a deeper understanding of the metastasis biology is key to developing better treatment strategies and achieving long-lasting therapeutic efficacies against breast cancer. This review covers recent breakthroughs in the discovery of various metastatic traits that contribute to the metastasis cascade of breast cancer, which may provide novel avenues for therapeutic targeting.
url https://doi.org/10.4137/BCBCR.S25460
work_keys_str_mv AT xinjin targetingbreastcancermetastasis
AT pingmu targetingbreastcancermetastasis
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