Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia

Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia

<p>Nucleophosmin (<i>NPM1</i>) gene mutations resulting in cytoplasmic delocalization of Nucleophosmin (NPMc+) are the most common genetic alteration in acute myeloid leukemia (AML). Here, we attempted to prepare monoclonal antibodies (mAbs) against <i>NPM1 </i>mutation...

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Bibliographic Details
Main Author: Shi Tan, Ling Zhang, Xiao-Ming Zhong, Zai-Lin Yang, Liu-Yang Zhao, Yu-Jie Gao, Hui-Yuan Shao, Feng-Xian Qin, Xian-Chun Chen, Hui-Juan Zhang, Hui Chen, Li Wang
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v08p0309.htm

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http://www.medsci.org/v08p0309.htm

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