Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor

Vitamin B12 is an essential micronutrient that functions in two metabolic pathways: the canonical propionate breakdown pathway and the methionine/S-adenosylmethionine (Met/SAM) cycle. In Caenorhabditis elegans, low vitamin B12, or genetic perturbation of the canonical propionate breakdown pathway re...

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Bibliographic Details
Main Authors: Gabrielle E Giese, Melissa D Walker, Olga Ponomarova, Hefei Zhang, Xuhang Li, Gregory Minevich, Albertha JM Walhout
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60259