Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
Kainate receptors are selectively found at CA3-mossy fibre synapses, although the mechanisms regulating this compartmentalisation have yet to be determined. Here, the authors find KAR segregation is dependent on the amount of GluK2a protein and an interaction between the GluK2 C-terminal domain and...
Main Authors: | Sabine Fièvre, Mario Carta, Ingrid Chamma, Virginie Labrousse, Olivier Thoumine, Christophe Mulle |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12738 |
Similar Items
-
Mécanismes moléculaires de la stabilisation synaptique des récepteurs du glutamate de type kaïnate dans les cellules pyramidales de CA3
by: Fievre, Sabine
Published: (2015) -
Protein kinase signalling requirements for metabotropic action of kainate receptors in rat CA1 pyramidal neurones
by: Grabauskas, Gintautas, et al.
Published: (2007) -
Metabotropic-mediated kainate receptor regulation of IsAHP and excitability in pyramidal cells
by: Melyan, Z., et al.
Published: (2002) -
Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice
by: Seil Jang, et al.
Published: (2020-12-01) -
Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history
by: Elsa Diguet, et al.
Published: (2004-04-01)