Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

Abstract Background Insulin-like growth factor-1 (IGF-1) acts on glucose and protein metabolism and human growth and also influences blood pressure and renal function. This study investigated whether the single-nucleotide polymorphism of IGF-1, rs35767, plays a role in metabolic syndrome indicators,...

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Bibliographic Details
Main Authors: Kosuke Honda, Satoru Kuriyama, Kimiyoshi Ichida, Tomoko Nakano, Naoki Sugano, Takashi Yokoo
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Nephrology
Subjects:
IGF-1
Gene polymorphism
Blood pressure
Glomerular filtration rate
Online Access:https://doi.org/10.1186/s12882-021-02408-9

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