Advances in RNAi-Assisted Strain Engineering in Saccharomyces cerevisiae

Advances in RNAi-Assisted Strain Engineering in Saccharomyces cerevisiae

Saccharomyces cerevisiae is a widely used eukaryotic model and microbial cell factory. RNA interference (RNAi) is a conserved regulatory mechanism among eukaryotes but absent from S. cerevisiae. Recent reconstitution of RNAi machinery in S. cerevisiae enables the use of this powerful tool for strain...

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Bibliographic Details
Main Authors: Yongcan Chen, Erpeng Guo, Jianzhi Zhang, Tong Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
RNAi
Saccharomyces cerevisiae
strain engineering
functional genomics
synthetic biology
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00731/full

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