Identification of transcriptome signature for myocardial reductive stress

The nuclear factor erythroid 2 like 2 (Nfe2l2/Nrf2) is a master regulator of antioxidant gene transcription. We recently identified that constitutive activation of Nrf2 (CaNrf2) caused reductive stress (RS) in the myocardium. Here we investigate how chronic Nrf2 activation alters myocardial mRNA tra...

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Bibliographic Details
Main Authors: Justin M. Quiles, Madhusudhanan Narasimhan, Timothy Mosbruger, Gobinath Shanmugam, David Crossman, Namakkal S. Rajasekaran
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717304998