MeCas12a, a Highly Sensitive and Specific System for COVID‐19 Detection

MeCas12a, a Highly Sensitive and Specific System for COVID‐19 Detection

Abstract Cas12a‐based systems, which detect specific nucleic acids via collateral cleavage of reporter DNA, display huge potentials for rapid diagnosis of infectious diseases. Here, the Manganese‐enhanced Cas12a (MeCas12a) system is described, where manganese is used to increase the detection sensit...

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Bibliographic Details
Main Authors: Peixiang Ma, Qingzhou Meng, Baoqing Sun, Bing Zhao, Lu Dang, Mingtian Zhong, Siyuan Liu, Hongtao Xu, Hong Mei, Jia Liu, Tian Chi, Guang Yang, Ming Liu, Xingxu Huang, Xinjie Wang
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Advanced Science
Subjects:
COVID‐19
CRISPR‐based detection
CRISPR/Cas12a
manganese
SARS‐CoV‐2
Online Access:https://doi.org/10.1002/advs.202001300

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