Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network

Aiming at the current problem of insufficient extraction of small retinal blood vessels, we propose a retinal blood vessel segmentation algorithm that combines supervised learning and unsupervised learning algorithms. In this study, we use a multiscale matched filter with vessel enhancement capabili...

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Main Authors: Yuliang Ma, Zhenbin Zhu, Zhekang Dong, Tao Shen, Mingxu Sun, Wanzeng Kong
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/5561125
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spelling doaj-5ee844e6dcaf4bbdb8165c65750431762021-06-07T02:14:07ZengHindawi LimitedBioMed Research International2314-61412021-01-01202110.1155/2021/5561125Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net NetworkYuliang Ma0Zhenbin Zhu1Zhekang Dong2Tao Shen3Mingxu Sun4Wanzeng Kong5Institute of Intelligent Control and RoboticsInstitute of Intelligent Control and RoboticsSchool of Electronics and InformationSchool of Electrical EngineeringSchool of Electrical EngineeringKey Laboratory of Brain Machine Collaborative Intelligence of Zhejiang ProvinceAiming at the current problem of insufficient extraction of small retinal blood vessels, we propose a retinal blood vessel segmentation algorithm that combines supervised learning and unsupervised learning algorithms. In this study, we use a multiscale matched filter with vessel enhancement capability and a U-Net model with a coding and decoding network structure. Three channels are used to extract vessel features separately, and finally, the segmentation results of the three channels are merged. The algorithm proposed in this paper has been verified and evaluated on the DRIVE, STARE, and CHASE_DB1 datasets. The experimental results show that the proposed algorithm can segment small blood vessels better than most other methods. We conclude that our algorithm has reached 0.8745, 0.8903, and 0.8916 on the three datasets in the sensitivity metric, respectively, which is nearly 0.1 higher than other existing methods.http://dx.doi.org/10.1155/2021/5561125
collection DOAJ
language English
format Article
sources DOAJ
author Yuliang Ma
Zhenbin Zhu
Zhekang Dong
Tao Shen
Mingxu Sun
Wanzeng Kong
spellingShingle Yuliang Ma
Zhenbin Zhu
Zhekang Dong
Tao Shen
Mingxu Sun
Wanzeng Kong
Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
BioMed Research International
author_facet Yuliang Ma
Zhenbin Zhu
Zhekang Dong
Tao Shen
Mingxu Sun
Wanzeng Kong
author_sort Yuliang Ma
title Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
title_short Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
title_full Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
title_fullStr Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
title_full_unstemmed Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network
title_sort multichannel retinal blood vessel segmentation based on the combination of matched filter and u-net network
publisher Hindawi Limited
series BioMed Research International
issn 2314-6141
publishDate 2021-01-01
description Aiming at the current problem of insufficient extraction of small retinal blood vessels, we propose a retinal blood vessel segmentation algorithm that combines supervised learning and unsupervised learning algorithms. In this study, we use a multiscale matched filter with vessel enhancement capability and a U-Net model with a coding and decoding network structure. Three channels are used to extract vessel features separately, and finally, the segmentation results of the three channels are merged. The algorithm proposed in this paper has been verified and evaluated on the DRIVE, STARE, and CHASE_DB1 datasets. The experimental results show that the proposed algorithm can segment small blood vessels better than most other methods. We conclude that our algorithm has reached 0.8745, 0.8903, and 0.8916 on the three datasets in the sensitivity metric, respectively, which is nearly 0.1 higher than other existing methods.
url http://dx.doi.org/10.1155/2021/5561125
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