The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews.
Most meta-analyses include data from one or more small studies that, individually, do not have power to detect an intervention effect. The relative influence of adequately powered and underpowered studies in published meta-analyses has not previously been explored. We examine the distribution of pow...
Main Authors: | Rebecca M Turner, Sheila M Bird, Julian P T Higgins |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3609745?pdf=render |
Similar Items
-
Characteristics of meta-analyses and their component studies in the <it>Cochrane Database of Systematic Reviews</it>: a cross-sectional, descriptive analysis
by: Davey Jonathan, et al.
Published: (2011-11-01) -
Heterogeneity in Cochrane and non-Cochrane meta-analyses in orthodontics
by: Fleming, P.S, et al.
Published: (2018) -
Unethical Conduct of Underpowered Clinical Trials
by: Farrokh Habibzadeh
Published: (2015-10-01) -
Current Incentives for Scientists Lead to Underpowered Studies with Erroneous Conclusions.
by: Andrew D Higginson, et al.
Published: (2016-11-01) -
COVID-19: underpowered randomised trials, or no randomised trials?
by: Atle Fretheim
Published: (2021-03-01)