Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies

Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies

Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. Prunetin (PRU) is an O-methylated flavonoid that belongs to the group of isoflavone executing beneficial activities. In the present study, we investigate...

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Bibliographic Details
Main Authors: Preethi Vetrivel, Seong Min Kim, Sang Eun Ha, Hun Hwan Kim, Pritam Bhagwan Bhosale, Kalaiselvi Senthil, Gon Sup Kim
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
prunetin
necroptosis
gastric cancer
RIPK3
molecular docking
dynamics
Online Access:https://www.mdpi.com/2218-273X/10/7/1086

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