Circulating miRNAs Associated With ER Stress and Organ Damage in a Preclinical Model of Trauma Hemorrhagic Shock

Circulating miRNAs Associated With ER Stress and Organ Damage in a Preclinical Model of Trauma Hemorrhagic Shock

Circulating microRNAs (miRNA) alterations have been reported in severe trauma patients but the pathophysiological relevance of these changes is still unclear. miRNAs are critical biologic regulators of pathological events such as hypoxia and inflammation, which are known to induce endoplasmic reticu...

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Bibliographic Details
Main Authors: Andreia Luís, Matthias Hackl, Mohammad Jafarmadar, Claudia Keibl, Julia M. Jilge, Johannes Grillari, Soheyl Bahrami, Andrey V. Kozlov
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Medicine
Subjects:
circulating miRNAs
trauma hemorrhagic shock
ER stress
organ damage
multiple organ dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.568096/full

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