Myelosuppression of Thrombocytes and Monocytes Is Associated with a Lack of Synergy between Chemotherapy and Anti-VEGF Treatment

Myelosuppression of Thrombocytes and Monocytes Is Associated with a Lack of Synergy between Chemotherapy and Anti-VEGF Treatment

Purpose: Chemotherapeutic agents that have shown improved patient outcome when combined with anti-vascular endothelial growth factor (VEGF) therapy were recently identified to induce the mobilization of proangiogenic Tie-2-expressing monocytes (TEMs) and endothelial progenitor cells (EPCs) by plate...

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Bibliographic Details
Main Authors: Patrick Starlinger, Philipp Brugger, Dominic Schauer, Silvia Sommerfeldt, Dietmar Tamandl, Irene Kuehrer, Sebastian F. Schoppmann, Michael Gnant, Christine Brostjan
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861180059X

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