Paradoxical effect of pertussis toxin on the delayed hypersensitivity response to autoantigens in mice.

Pertussis toxin (PTX), an exotoxin of Bordetella pertussis, enhances the development of experimental autoimmune diseases such as experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE) in rodent models. The mechanisms of the promotion of experimental autoimmune dise...

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Bibliographic Details
Main Authors: Rajwahrdhan Yadav, Sourojit Bhowmick, Philip Gorecki, James O'Rourke, Robert E Cone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2916836?pdf=render