Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion
Clonal selection and transcriptional reprogramming (e.g., epithelial-mesenchymal transition or phenotype switching) are the predominant theories thought to underlie tumor progression. However, a “division of labor” leading to cooperation among tumor-cell subpopulations could be an additional catalys...
Main Authors: | Anna Chapman, Laura Fernandez del Ama, Jennifer Ferguson, Jivko Kamarashev, Claudia Wellbrock, Adam Hurlstone |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-08-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714005294 |
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