Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein.

The synucleins are a family of natively unstructured proteins consisting of α-, β-, and γ-synuclein which are primarily expressed in neurons. They have been linked to a wide variety of pathologies, including neurological disorders, such as Parkinson's disease (α-synuclein) and dementia with Lew...

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Bibliographic Details
Main Authors: Vanessa C Ducas, Elizabeth Rhoades
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904966?pdf=render

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