Optogenetic Activation of the Excitatory Neurons Expressing CaMKIIα in the Ventral Tegmental Area Upregulates the Locomotor Activity of Free Behaving Rats

Optogenetic Activation of the Excitatory Neurons Expressing CaMKIIα in the Ventral Tegmental Area Upregulates the Locomotor Activity of Free Behaving Rats

The ventral tegmental area (VTA) plays an important role in motivation and motor activity of mammals. Previous studies have reported that electrical stimulations of the VTA’s neuronal projections were able to upregulate the locomotor activity of behaving rats. However, which types of neurons in the...

Full description

Bibliographic Details
Main Authors:	Songchao Guo, Sicong Chen, Qiaosheng Zhang, Yueming Wang, Kedi Xu, Xiaoxiang Zheng
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2014/687469

Similar Items

Mechanisms of CaMKII Activation
by: Jeffrey R Erickson
Published: (2014-04-01)

Optogenetic Activation of a Lateral Hypothalamic-Ventral Tegmental Drive-Reward Pathway.
by: Eduardo D Gigante, et al.
Published: (2016-01-01)

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia
by: Taylor, Norman, et al.
Published: (2017)

Conjunctive processing of locomotor signals by the ventral tegmental area neuronal population.
by: Dong V Wang, et al.
Published: (2011-01-01)

The CaMKII holoenzyme structure in activation-competent conformations
by: Janette B. Myers, et al.
Published: (2017-06-01)

CaMKII Activity in the Inflammatory Response of Cardiac Diseases
by: Maria Rosaria Rusciano, et al.
Published: (2019-09-01)

Activation of Orexin System Stimulates CaMKII Expression
by: Yuanyuan Fan, et al.
Published: (2021-07-01)

Long-Term Depression of Excitatory Inputs to GABAergic Neurons in the Ventral Tegmental Area
by: Sandoval, Philip J.
Published: (2012)

The role of CaMKII regulation of phospholamban activity in heart disease
by: Alicia eMattiazzi, et al.
Published: (2014-01-01)

Spectroscopic Study of the Conformational Changes Involved in the Activation of CaMKII
by: Rodriguez Mena, Francisco Guillermo
Published: (2016)

In vivo visualization of CaMKII activity in ocular dominance plasticity
by: Kwok, Show Ming
Published: (2009)

CaMKII in Cardiac Health and Disease
Published: (2014)

Freely Behaving Mice Can Brake and Turn During Optogenetic Stimulation of the Mesencephalic Locomotor Region
by: Cornelis Immanuel van der Zouwen, et al.
Published: (2021-04-01)

Changes in locomotor activity and body temperature induced by morphine in the ventral tegmental area of the rat brain : conditioned and unconditioned effect
by: Vezina, Paul
Published: (1983)

Activity-dependent redistribution of CaMKII in the postsynaptic compartment of hippocampal neurons
by: Jung-Hwa Tao-Cheng
Published: (2020-04-01)

CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density.
by: Soe Thein, et al.
Published: (2014-01-01)

Optogenetic/Chemogenetic Activation of GABAergic Neurons in the Ventral Tegmental Area Facilitates General Anesthesia via Projections to the Lateral Hypothalamus in Mice
by: Lu Yin, et al.
Published: (2019-11-01)

CaMKII regulation of cardiac K channels
by: Julian eMustroph, et al.
Published: (2014-02-01)

CaMKII and stress mix it up in mitochondria
by: Olha M Koval, et al.
Published: (2014-05-01)

Regulation of CaMKII signaling in cardiovascular disease
by: Mariya Yordanova Mollova, et al.
Published: (2015-08-01)

CaMKII in sinoatrial node physiology and dysfunction
by: Yuejin eWu, et al.
Published: (2014-03-01)

CASK and CaMKII function in Drosophila memory
by: Bilal eMalik, et al.
Published: (2014-06-01)

CaMKII regulation of astrocytic glutamate uptake
by: Chawla, Aarti R.
Published: (2016)

The effects of CaMKII signaling on neuronal viability
by: Ashpole, Nicole M.
Published: (2013)

The Role of CaMKII and ERK Signaling in Addiction
by: Wenbin Jia, et al.
Published: (2021-03-01)

Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation
by: Moitrayee Bhattacharyya, et al.
Published: (2020-03-01)

Correction: Publisher Correction: The CaMKII holoenzyme structure in activation-competent conformations
by: Janette B. Myers, et al.
Published: (2018-05-01)

Correction: CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density
by: The Staff
Published: (2014-01-01)

NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis
by: Jingyi Zhou, et al.
Published: (2020-09-01)

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity.
by: Shubha Murthy, et al.
Published: (2017-01-01)

A T-type channel-calmodulin complex triggers αCaMKII activation
by: Hadhimulya Asmara, et al.
Published: (2017-08-01)

Correction: CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density.
Published: (2014-01-01)

CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
by: Liu, Pin-Wu
Published: (2021)

RIPK3-Mediated Necroptosis in Diabetic Cardiomyopathy Requires CaMKII Activation
by: Yun Chen, et al.
Published: (2021-01-01)

Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability.
by: Jason R Klug, et al.
Published: (2012-01-01)

Age-dependent effects of methylphenidate on locomotor sensitization and Netrin-1 receptor expression in the ventral tegmental area
by: Almey, Anne
Published: (2009)

Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
by: Margaret Stratton, et al.
Published: (2014-01-01)

Effects of blockade of muscarinic receptors in the ventral tegmental area : attenuation of cocaine reward, but enhancement of locomotor activity and dopamine overflow in the nucleus accumbens
by: Munn, Elizabeth M
Published: (1999)

Resonance in the Mouse Ventral Tegmental Area Dopaminergic Network Induced by Regular and Poisson Distributed Optogenetic Stimulation in-vitro
by: Luuk van der Velden, et al.
Published: (2020-02-01)

Memories Are Made of This: Modeling the CaMKII Molecular Switch
Published: (2005-01-01)