Phospholipid derived mediators and glomerulonephritis

The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism wou...

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Bibliographic Details
Main Author: E. N. Wardle
Format: Article
Language:English
Published: Hindawi Limited 1993-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935193000134