LRP12 silencing during brain development results in cortical dyslamination and seizure sensitization

Correct positioning and differentiation of neurons during brain development is a key precondition for proper function. Focal cortical dysplasias (FCDs) are increasingly recognized as causes of therapy refractory epilepsies. Neuropathological analyses of respective surgical specimens from neurosurger...

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Bibliographic Details
Main Authors: Alexander Grote, Barbara K. Robens, Ingmar Blümcke, Albert J. Becker, Susanne Schoch, Eva Gembé
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300991