Immunotherapy for liver tumors: present status and future prospects

<p>Abstract</p> <p>Increasing evidence suggests that immune responses are involved in the control of cancer and that the immune system can be manipulated in different ways to recognize and attack tumors. Progress in immune-based strategies has opened new therapeutic avenues using a...

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Bibliographic Details
Main Authors: Gidekel Manuel, Atorrasagasti Catalina, Malvicini Mariana, Aquino Jorge B, Rozados Viviana, Alaniz Laura, Matar Pablo, Silva Marcelo, Scharovsky O Graciela, Mazzolini Guillermo
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/30
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Summary:<p>Abstract</p> <p>Increasing evidence suggests that immune responses are involved in the control of cancer and that the immune system can be manipulated in different ways to recognize and attack tumors. Progress in immune-based strategies has opened new therapeutic avenues using a number of techniques destined to eliminate malignant cells. In the present review, we overview current knowledge on the importance, successes and difficulties of immunotherapy in liver tumors, including preclinical data available in animal models and information from clinical trials carried out during the lasts years. This review shows that new options for the treatment of advanced liver tumors are urgently needed and that there is a ground for future advances in the field.</p>
ISSN:1021-7770
1423-0127