Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels

Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mic...

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Bibliographic Details
Main Authors: Yuanyuan Li, Zhaochong Cai, Shunjie Liu, Haoke Zhang, Sherman T. H. Wong, Jacky W. Y. Lam, Ryan T. K. Kwok, Jun Qian, Ben Zhong Tang
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15095-1
Description
Summary:Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mice.
ISSN:2041-1723