Short-term outcome of Boston Type 1 keratoprosthesis for bilateral limbal stem cell deficiency

• Main Authors: Sayan Basu, Mukesh Taneja, Raja Narayanan, Sirisha Senthil, Virender S Sangwan
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2012-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: Orbit; proptosis; thyroid; Hyperhomocysteinemia; retinal arterial occlusions; systemic associations; young age; Illumination; letter charts; visual acuity; Dacryocystorhinostomy; intraocular pressure; systemic effects; timolol maleate; Accommodation; dynamic retinoscopy; ophthalmoscopy; photorefraction; photoretinoscopy; Apoptosis; corneal epithelium; formulation; sphingosine-1 phosphate; Digital camera; external photograph; photography; Android; eye handbook; iPhone; smart phone; testing tools; Anterior chamber intraocular lens; gyrate atrophy; posterior dislocation of intraocular lens; psuedophakia; Conjunctival ulcer; conjunctivitis; Stenotrophomonas maltophilia; Adrenergic blocker; imipramine; intraoperative floppy iris syndrome; iris hooks; phacoemulsification; Corneal ectasia; deep anterior lamellar keratoplasty; hexagonal keratotomy; hyperopia; Intravitreal triamcinolone acetonide; retinochoroiditis; toxoplasmosis; Capsulorrhexis; completion rates; pediatric cataract surgery; Complications; knotless scleral fixated intraocular lens; technique; Bilateral abducens nerve; delayed onset paresis; head injury; Boston keratoprosthesis; limbal stem cell deficiency
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=2;spage=151;epage=153;aulast=Basu

This study reports the short-term functional and anatomical outcome of Boston Type 1 keratoprosthesis (Boston Kpro) implantation for bilateral limbal stem cell deficiency (LCSD). Retrospective analysis was done on eight eyes of eight patients who underwent Boston Kpro implantation between July 2009 and October 2009. The best corrected visual acuity (BCVA) and slit-lamp biomicroscopy findings were assessed at 1, 3 and 6 months postoperatively. All eight eyes retained the prosthesis. BCVA of 20/40 or better was achieved in 8, 6, and 5 eyes at 1, 3, and 6 months, respectively, postoperatively. One patient each developed epithelial defect, sterile stromal melt and fungal keratitis in the late postoperative period associated with antecedent loss of the soft contact lens from the eye. Boston Kpro has good short-term visual and anatomical outcome in patients with bilateral LSCD, provided compliance with postoperative care can be ensured.