Hidden suppressive interactions are common in higher-order drug combinations
Summary: The rapid increase of multi-drug resistant bacteria has led to a greater emphasis on multi-drug combination treatments. However, some combinations can be suppressive—that is, bacteria grow faster in some drug combinations than when treated with a single drug. Typically, when studying intera...
Main Authors: | Natalie Ann Lozano-Huntelman, April Zhou, Elif Tekin, Mauricio Cruz-Loya, Bjørn Østman, Sada Boyd, Van M. Savage, Pamela Yeh |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221003230 |
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