Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

Regenerative medicine: lacrimal gland epithelium in vitro One possible approach to treat dry eye diseases is to transplant lacrimal glands generated in vitro from human embryonic stem cells into patients. As a first step, we developed a novel method to generate lacrimal gland epithelium-like cells....

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Main Authors: Masatoshi Hirayama, Shigeru B.H. Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K. Goparaju, Atsumi Soma, Yuhki Nakatake, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeto Shimmura, Kazuo Tsubota, Minoru S.H. Ko
Format: Article
Language:English
Published: Nature Publishing Group 2017-01-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-016-0001-8