PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology

Abstract Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis...

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Main Authors: M. Sollini, L. Cozzi, L. Antunovic, A. Chiti, M. Kirienko
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00426-y
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spelling doaj-5e580add21d94781b7a7baa0c269c8c82020-12-08T01:58:20ZengNature Publishing GroupScientific Reports2045-23222017-03-017111510.1038/s41598-017-00426-yPET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodologyM. Sollini0L. Cozzi1L. Antunovic2A. Chiti3M. Kirienko4Department of Biomedical Sciences, Humanitas UniversityDepartment of Biomedical Sciences, Humanitas UniversityNuclear Medicine Unit, Humanitas Clinical and Research CenterDepartment of Biomedical Sciences, Humanitas UniversityDepartment of Biomedical Sciences, Humanitas UniversityAbstract Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis which provides an “in-vivo” lesion characterization, and predictive information in several malignances including NSCLC; however several drawbacks and limitations affect these studies, especially because of lack of standardization in features calculation, definitions and methodology reporting. The present paper provides a comprehensive review of literature describing the state-of-the-art of FDG-PET/CT texture analysis in NSCLC, suggesting a proposal for harmonization of methodology.https://doi.org/10.1038/s41598-017-00426-y
collection DOAJ
language English
format Article
sources DOAJ
author M. Sollini
L. Cozzi
L. Antunovic
A. Chiti
M. Kirienko
spellingShingle M. Sollini
L. Cozzi
L. Antunovic
A. Chiti
M. Kirienko
PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
Scientific Reports
author_facet M. Sollini
L. Cozzi
L. Antunovic
A. Chiti
M. Kirienko
author_sort M. Sollini
title PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
title_short PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
title_full PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
title_fullStr PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
title_full_unstemmed PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology
title_sort pet radiomics in nsclc: state of the art and a proposal for harmonization of methodology
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2017-03-01
description Abstract Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis which provides an “in-vivo” lesion characterization, and predictive information in several malignances including NSCLC; however several drawbacks and limitations affect these studies, especially because of lack of standardization in features calculation, definitions and methodology reporting. The present paper provides a comprehensive review of literature describing the state-of-the-art of FDG-PET/CT texture analysis in NSCLC, suggesting a proposal for harmonization of methodology.
url https://doi.org/10.1038/s41598-017-00426-y
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