Direct Observation of Growth Rate Dispersion in the Enzymatic Reactive Crystallization of Ampicillin

Prediction and control of crystal size distributions, a prerequisite for production of consistent crystalline material in the pharmaceutical industry, requires knowledge of potential non-idealities of crystal growth. Ampicillin is one such medicine consumed in crystal form (ampicillin trihydrate). T...

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Bibliographic Details
Main Authors: Matthew A. McDonald, Andreas S. Bommarius, Martha A. Grover, Ronald W. Rousseau
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/7/6/390