The therapeutic potential of colchicine in the complications of COVID19. Could the immunometabolic properties of an old and cheap drug help?

The present study analyzes the importance of the inflammasome that involves the NLRP3 complex in the state of hypercytokinemia observed in patients with COVID-19, significantly increasing IL-1β, IL18, IL-6, and TNF. Unfortunately, improving the immune response can sometimes worsen the outcome of the...

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Bibliographic Details
Main Authors: Sandro Augusto Ribeiro, Cassio Lopes, Ricardo Amaral, Adilaine Amaral
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Metabolism Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936820300256

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