A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans

A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans

Regulation of animal development in response to nutritional cues is an intensely studied problem related to disease and aging. While extensive studies indicated roles of the Target of Rapamycin (TOR) in sensing certain nutrients for controlling growth and metabolism, the roles of fatty acids and lip...

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Bibliographic Details
Main Authors: Huanhu Zhu, Huali Shen, Aileen K Sewell, Marina Kniazeva, Min Han
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-05-01
Series:eLife
Subjects:
branched-chain fatty acid
growth arrest
nutrient sensing
NPRL
glucosylceramide
target of rapamycin
Online Access:https://elifesciences.org/articles/00429

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