Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

van Haaften et al. show numerical-experimental approach to reconstruct the graft–host response. They interrogate the mechanoregulation in dialysis grafts to solve the disturbed shear stress problem, which can be a cause of neointimal hyperplasia in blood vessels and grafts.

Bibliographic Details
Main Authors: Eline E. van Haaften, Sjeng Quicken, Wouter Huberts, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02065-6
Description
Summary:van Haaften et al. show numerical-experimental approach to reconstruct the graft–host response. They interrogate the mechanoregulation in dialysis grafts to solve the disturbed shear stress problem, which can be a cause of neointimal hyperplasia in blood vessels and grafts.
ISSN:2399-3642