Alantolactone inhibits stem-like cell phenotype, chemoresistance and metastasis in PC3 cells through STAT3 signaling pathway

Background and purpose: Cancer stem cells (CSCs), as the subpopulation of cancer cells, are associated with carcinogenesis, chemoresistance, and metastasis in malignancies. Also, CSCs are considered as the major reason for treatment failure in prostate cancer (PCa). Alantolactone (ALT), exerts antic...

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Bibliographic Details
Main Authors: Ghader Babaei, Mohammad Hassan Khadem Ansari, Shiva Gholizadeh-Ghaleh Aziz, Masoumeh Rajabi Bazl
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2020;volume=15;issue=6;spage=551;epage=562;aulast=Babaei