A Novel Ex Vivo System Using 3D Polymer Scaffold to Culture Circulating Tumor Cells from Breast Cancer Patients Exhibits Dynamic E-M Phenotypes

A Novel Ex Vivo System Using 3D Polymer Scaffold to Culture Circulating Tumor Cells from Breast Cancer Patients Exhibits Dynamic E-M Phenotypes

The majority of the cancer-associated deaths is due to metastasis—the spread of tumors to other organs. Circulating tumor cells (CTCs), which are shed from the primary tumor into the circulation, serve as precursors of metastasis. CTCs have now gained much attention as a new prognostic and...

Full description

Bibliographic Details
Main Authors: Tamasa De, Shina Goyal, Gowri Balachander, Kaushik Chatterjee, Prashant Kumar, Govind Babu K., Annapoorni Rangarajan
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Journal of Clinical Medicine
Subjects:
circulating tumor cells (CTCs)
breast cancer
3D culture
epithelial-mesenchymal heterogeneity
Online Access:https://www.mdpi.com/2077-0383/8/9/1473

Similar Items

Similar Items