Evolving Role of Bone Biomarkers in Castration-Resistant Prostate Cancer

The preferential metastasis of prostate cancer cells to bone disrupts the process of bone remodeling and results in lesions that cause significant pain and patient morbidity. Although prostate-specific antigen (PSA) is an established biomarker in prostate cancer, it provides only limited informatio...

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Bibliographic Details
Main Authors: Janet E. Brown, Sheryl Sim
Format: Article
Language:English
Published: Elsevier 2010-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800703